Journal :   International Journal of Technology

Volume No. :   9

Issue No. :  2

Year :  2019

Pages :   45-53

ISSN Print :  2231-3907

ISSN Online :  2231-3915


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Analytical Method for Determination of Thiocolchicoside in marketed Pharmaceutical Preparation: A Review



Address:   Jadhav Ankush P.*, Datar P.A., Shete R.V.
Department of Pharmaceutical Quality Assurance, Rajgad Dnyanpeeth’s College of Pharmacy, Bhor-Pune, Maharashtra, Pin-412206.
*Corresponding Author
DOI No: 10.5958/2231-3915.2019.00011.7

ABSTRACT:
Thiocolchicoside a natural anti-inflammatory glycoside. It is the semi-synthetic derivative of the colchicine. It is a muscle relaxant with anti-inflammatory and analgesic effects. It works through selective binding to the GABA-A receptor. It prevents muscle contractions by activating the GABA inhibitory motor pathway. The article summarizes analytical method including the chromatographic method, LC-MS (Liquid Chromatography-mass spectroscopy), HPLC, GC-MS (Gas chromatography-mass spectroscopy), HPTLC and UV-Visible spectrophotometry techniques for estimation of Thiocolchicoside in biological samples, bulk and pharmaceutical formulation.
KEYWORDS:
Thiocolchicoside (THC); UV-Spectrophotometry; HPLC; HPTLC; LC-MS; GC-MS.
Cite:
Jadhav Ankush P., Datar P.A., Shete R.V. Analytical Method for Determination of Thiocolchicoside in marketed Pharmaceutical Preparation: A Review. Int. J. Tech. 2019; 9(2):45-53.
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